Chronic migraine is a debilitating condition affecting millions worldwide. Conventional treatments often provide only partial relief, leaving many sufferers seeking alternative therapies. Stem cell therapy has emerged as a promising solution for chronic migraine management, offering the potential for long-term pain reduction and improved quality of

protection and efficacy of MSC-EVs in different sickness circumstances need to be ensured in additional preclinical and medical analysis. In vivo distribution Assessment of fluorescence-labeled EVs has revealed that MSC-EVs may need homing ability for wounded or tumor-bearing web-sites similar as MSCs [202]. so far, the scientific trials with MSCs

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